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Protein farnesylation is requisite for mitochondrial fuel-induced insulin release: Further evidence to link reactive oxygen species generation to insulin secretion in pancreatic β-cells

Several lines of recent evidence implicate regulatory roles for reactive oxygen species (ROS) in islet function and insulin secretion. The phagocyte-like NADPH oxidase (Nox2) has recently been shown to be one of the sources of ROS in the signaling events leading to glucose stimulated insulin secreti...

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Detalhes bibliográficos
Main Authors: Matti, Andrea, Kyathanahalli, Chandrashekara, Kowluru, Anjaneyulu
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365803/
https://ncbi.nlm.nih.gov/pubmed/22504835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.19121
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