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Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ Light Chain Enhancer of Activated B Cells (NFκB) Signaling Controls Basal and DNA Damage-induced Transglutaminase 2 Expression

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme that cross-links proteins and its overexpression, linked to a drug resistant phenotype, is commonly observed in cancer cells. Further, up-regulation of TG2 expression occurs during response to various forms of cell stress; however, the mole...

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Autores principales: Ai, Lingbao, Skehan, Ryan R., Saydi, John, Lin, Tong, Brown, Kevin D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365769/
https://ncbi.nlm.nih.gov/pubmed/22493284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339317
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