Nanog Increases Focal Adhesion Kinase (FAK) Promoter Activity and Expression and Directly Binds to FAK Protein to Be Phosphorylated

Nanog and FAK were shown to be overexpressed in cancer cells. In this report, the Nanog overexpression increased FAK expression in 293, SW480, and SW620 cancer cells. Nanog binds the FAK promoter and up-regulates its activity, whereas Nanog siRNA decreases FAK promoter activity and FAK mRNA. The FAK...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ho, Baotran, Olson, Gretchen, Figel, Sheila, Gelman, Irwin, Cance, William G., Golubovskaya, Vita M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365765/
https://ncbi.nlm.nih.gov/pubmed/22493428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322883
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak