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Reduced DNA topoisomerase II activity in ataxia-telangiectasia cells.

Considerable evidence supports a defect at the level of chromatin structure or recognition of that structure in cells from patients with the human genetic disorder ataxia-telangiectasia. Accordingly, we have investigated the activities of enzymes that alter the topology of DNA in Epstein Barr Virus-...

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Autores principales: Singh, S P, Mohamed, R, Salmond, C, Lavin, M F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC336565/
https://ncbi.nlm.nih.gov/pubmed/2836804
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