Osteopontin in Systemic Sclerosis and its Role in Dermal Fibrosis

Osteopontin (OPN) is a matricellular protein with proinflammatory and profibrotic properties. Previous reports demonstrate a role for OPN in wound healing and pulmonary fibrosis. Herein, we determined if OPN levels are increased in a large cohort of systemic sclerosis (SSc) patients and if OPN contr...

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Detalhes bibliográficos
Main Authors: Wu, Minghua, Schneider, Daniel J., Mayes, Maureen D, Assassi, Shervin, Arnett, Frank C., Tan, Filemon K., Blackburn, Michael R., Agarwal, Sandeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365548/
https://ncbi.nlm.nih.gov/pubmed/22402440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.32
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