Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts

INTRODUCTION: Increased levels of genes in the type I interferon (IFN) pathway have been observed in patients with systemic sclerosis (SSc), or scleroderma. How type I IFN regulates the dermal fibroblast and its participation in the development of dermal fibrosis is not known. We hypothesized that o...

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Detalhes bibliográficos
Main Authors: Agarwal, Sandeep K, Wu, Minghua, Livingston, Christopher K, Parks, Donald H, Mayes, Maureen D, Arnett, Frank C, Tan, Filemon K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241348/
https://ncbi.nlm.nih.gov/pubmed/21223583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3221
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