Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosis

OBJECTIVES: There is considerable evidence that implicates dysregulation of type I interferon signaling (or type I IFN signature) in the pathogenesis of systemic sclerosis (SSc). Interferon regulatory factor 7 (IRF7) has been recognised as a master regulator of type I IFN signalling. The objective o...

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Publicado en:Ann Rheum Dis
Autores principales: Wu, Minghua, Skaug, Brian, Bi, Xiongjie, Mills, Tingting, Salazar, Gloria, Zhou, Xiaodong, Reveille, John, Agarwal, Sandeep K, Blackburn, Michael R, Mayes, Maureen D, Assassi, Shervin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167109/
https://ncbi.nlm.nih.gov/pubmed/31439591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215208
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