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Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS

Different viruses trigger pattern recognition receptor systems, such as Toll-like receptors or cytosolic RIG-I like helicases (RLH), and thus induce early type I interferon (IFN-I) responses. Such responses may confer protection until adaptive immunity is activated to an extent that the pathogen can...

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Detalhes bibliográficos
Main Authors: Kalinke, Ulrich, Prinz, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365287/
https://ncbi.nlm.nih.gov/pubmed/22430251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2012.8
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