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Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis

The homeostasis of naive T cells is essential for protective immunity against infection, but the cell-intrinsic molecular mechanisms that control naïve T-cell homeostasis are poorly understood. Genetic ablation in lower organisms has revealed a critical role for Vps34, an evolutionary conserved clas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Willinger, Tim, Flavell, Richard A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365213/
https://ncbi.nlm.nih.gov/pubmed/22592798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205305109
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