Real-time analysis and selection of methylated DNA by fluorescence-activated single molecule sorting in a nanofluidic channel

Epigenetic modifications, such as DNA and histone methylation, are responsible for regulatory pathways that affect disease. Current epigenetic analyses use bisulfite conversion to identify DNA methylation and chromatin immunoprecipitation to collect molecules bearing a specific histone modification....

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Detaylı Bibliyografya
Asıl Yazarlar: Cipriany, Benjamin R., Murphy, Patrick J., Hagarman, James A., Cerf, Aline, Latulippe, David, Levy, Stephen L., Benítez, Jaime J., Tan, Christine P., Topolancik, Juraj, Soloway, Paul D., Craighead, Harold G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365150/
https://ncbi.nlm.nih.gov/pubmed/22586076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117549109
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