Llwytho...

Single DNA Molecule Patterning for High-Throughput Epigenetic Mapping

We present a method for profiling the 5-methyl cytosine distribution on single DNA molecules. Our method combines soft-lithography and molecular elongation to form ordered arrays of more than 250,000 individual DNA molecules immobilized on a solid substrate. The methylation state of the DNA is detec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cerf, Aline, Cipriany, Benjamin R., Benítez, Jaime J., Craighead, Harold G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773698/
https://ncbi.nlm.nih.gov/pubmed/21981444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202506j
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