The Molecular Mechanism of Action of the CR6261-Azichromycin Combination Found through Computational Analysis

BACKGROUND: CR6261 was found in 2008 and F10 was found in 2009. In 2010 Friesen et al experimentally showed that Oseltamivir/Zanamivir may improve the therapeutic efficacy of CR6261. As a result, the use of CR6261 combined with a drug to provide an antibody-based therapy against all influenza A viru...

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Bibliographic Details
Main Authors: Cui, Wei, Wang, Kui, Ruan, Jishou, Qi, Zhi, Feng, Yi, Shao, Yiming, Tuszynski, Jack A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365099/
https://ncbi.nlm.nih.gov/pubmed/22693576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037790
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