Computable Features Required to Evaluate the Efficacy of Drugs and a Universal Algorithm to Find Optimally Effective Drug in a Drug Complex

BACKGROUND: The H1N1 pandemic in 2009 and the H5N1 pandemic in 2005 demonstrated that the drugs approved to treat influenza A viruses have low efficacy. This provided a stimulus for new studies of influenza A viruses in the context of the methods used in drug design developed over the past 100 years...

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Main Authors: Wang, Kui, Cui, Wei, Hu, Gang, Gao, Jianzhao, Wu, Zhonghua, Qiu, Xingye, Ruan, Jishou, Feng, Yi, Qi, Zhi, Shao, Yiming, Tuszynski, Jack A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311648/
https://ncbi.nlm.nih.gov/pubmed/22457784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033709
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