An Accurate Method for Prediction of Protein-Ligand Binding Site on Protein Surface Using SVM and Statistical Depth Function

Since proteins carry out their functions through interactions with other molecules, accurately identifying the protein-ligand binding site plays an important role in protein functional annotation and rational drug discovery. In the past two decades, a lot of algorithms were present to predict the pr...

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Hlavní autoři: Wang, Kui, Gao, Jianzhao, Shen, Shiyi, Tuszynski, Jack A., Ruan, Jishou, Hu, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806129/
https://ncbi.nlm.nih.gov/pubmed/24195070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/409658
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