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Carbene footprinting accurately maps binding sites in protein–ligand and protein–protein interactions

Specific interactions between proteins and their binding partners are fundamental to life processes. The ability to detect protein complexes, and map their sites of binding, is crucial to understanding basic biology at the molecular level. Methods that employ sensitive analytical techniques such as...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Manzi, Lucio, Barrow, Andrew S., Scott, Daniel, Layfield, Robert, Wright, Timothy G., Moses, John E., Oldham, Neil J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116083/
https://ncbi.nlm.nih.gov/pubmed/27848959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13288
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