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Specific Recognition of p53 Tetramers by Peptides Derived from p53 Interacting Proteins

Oligomerization plays a major role in regulating the activity of many proteins, and in modulating their interactions. p53 is a homotetrameric transcription factor that has a pivotal role in tumor suppression. Its tetramerization domain is contained within its C-terminal domain, which is a site for n...

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Detalhes bibliográficos
Main Authors: Gabizon, Ronen, Brandt, Tobias, Sukenik, Shahar, Lahav, Noa, Lebendiker, Mario, Shalev, Deborah E., Veprintsev, Dmitry, Friedler, Assaf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365014/
https://ncbi.nlm.nih.gov/pubmed/22693587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038060
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