Acetylation of Lysine 382 and Phosphorylation of Serine 392 in p53 Modulate the Interaction between p53 and MDC1 In Vitro

Occurrence of DNA damage in a cell activates the DNA damage response, a survival mechanism that ensures genomics stability. Two key members of the DNA damage response are the tumor suppressor p53, which is the most frequently mutated gene in cancers, and MDC1, which is a central adaptor that recruit...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Shahar, Or David, Gabizon, Ronen, Feine, Oren, Alhadeff, Raphael, Ganoth, Assaf, Argaman, Liron, Shimshoni, Elee, Friedler, Assaf, Goldberg, Michal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806821/
https://ncbi.nlm.nih.gov/pubmed/24194938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078472
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi