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Tumor Necrosis Factor α Inhibits Expression of the Iron Regulating Hormone Hepcidin in Murine Models of Innate Colitis

BACKGROUND: Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control hepcidin expression during states of i...

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Bibliografiske detaljer
Main Authors: Shanmugam, Nanda Kumar N., Ellenbogen, Shiri, Trebicka, Estela, Wang, Lijian, Mukhopadhyay, Subhankar, Lacy-Hulbert, Adam, Gallini, Carey Ann, Garrett, Wendy S., Cherayil, Bobby J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365004/
https://ncbi.nlm.nih.gov/pubmed/22675442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038136
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