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Serum-induced up-regulation of hepcidin expression involves the bone morphogenetic protein signaling pathway

Hepcidin is a peptide hormone that is secreted by the liver and that functions as the central regulator of systemic iron metabolism in mammals. Its expression is regulated at the transcriptional level by changes in iron status and iron requirements, and by inflammatory cues. There is considerable in...

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Hlavní autoři: Shanmugam, Nanda Kumar N., Cherayil, Bobby J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850278/
https://ncbi.nlm.nih.gov/pubmed/24157792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.10.065
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