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Staphylococcus aureus Surface Protein SdrE Binds Complement Regulator Factor H as an Immune Evasion Tactic

Similar to other highly successful invasive bacterial pathogens, Staphylococcus aureus recruits the complement regulatory protein factor H (fH) to its surface to inhibit the alternative pathway of complement. Here, we report the identification of the surface-associated protein SdrE as a fH-binding p...

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Autores principales: Sharp, Julia A., Echague, Charlene G., Hair, Pamela S., Ward, Michael D., Nyalwidhe, Julius O., Geoghegan, Joan A., Foster, Timothy J., Cunnion, Kenji M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364985/
https://ncbi.nlm.nih.gov/pubmed/22675461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038407
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