Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel ‘close, dock, lock and latch' mechanism for complement evasion

Complement factor H (CFH) is a soluble complement regulatory protein essential for the down-regulation of the alternative pathway on interaction with specific markers on the host cell surface. It recognizes the complement component 3b (C3b) and 3d (C3d) fragments in addition to self cell markers (i....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem J
Main Authors: Zhang, Yingjie, Wu, Minhao, Hang, Tianrong, Wang, Chengliang, Yang, Ye, Pan, Weimin, Zang, Jianye, Zhang, Min, Zhang, Xuan
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415847/
https://ncbi.nlm.nih.gov/pubmed/28258151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170085
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