Transcriptional Profiling of Human Brain Endothelial Cells Reveals Key Properties Crucial for Predictive In Vitro Blood-Brain Barrier Models

Brain microvascular endothelial cells (BEC) constitute the blood-brain barrier (BBB) which forms a dynamic interface between the blood and the central nervous system (CNS). This highly specialized interface restricts paracellular diffusion of fluids and solutes including chemicals, toxins and drugs...

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Detalhes bibliográficos
Main Authors: Urich, Eduard, Lazic, Stanley E., Molnos, Juliette, Wells, Isabelle, Freskgård, Per-Ola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364980/
https://ncbi.nlm.nih.gov/pubmed/22675443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038149
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