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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
The Blood-Brain Barrier (BBB) restricts access of large molecules to the brain. The low endocytic activity of brain endothelial cells (BECs) is believed to limit delivery of immunoglobulins (IgG) to the brain parenchyma. Here, we report that endogenous mouse IgG are localized within intracellular ve...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858719/ https://ncbi.nlm.nih.gov/pubmed/27149947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25658 |
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