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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
The Blood-Brain Barrier (BBB) restricts access of large molecules to the brain. The low endocytic activity of brain endothelial cells (BECs) is believed to limit delivery of immunoglobulins (IgG) to the brain parenchyma. Here, we report that endogenous mouse IgG are localized within intracellular ve...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858719/ https://ncbi.nlm.nih.gov/pubmed/27149947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25658 |
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