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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
The Blood-Brain Barrier (BBB) restricts access of large molecules to the brain. The low endocytic activity of brain endothelial cells (BECs) is believed to limit delivery of immunoglobulins (IgG) to the brain parenchyma. Here, we report that endogenous mouse IgG are localized within intracellular ve...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858719/ https://ncbi.nlm.nih.gov/pubmed/27149947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25658 |
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