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A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding

We have adapted an in vitro model of the human blood-brain barrier, the immortalized human cerebral microvascular endothelial cells (hCMEC/D3), to quantitatively measure protein transcytosis. After validating the receptor-mediated transport using transferrin, the system was used to measure transcyto...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sade, Hadassah, Baumgartner, Claudia, Hugenmatter, Adrian, Moessner, Ekkehard, Freskgård, Per-Ola, Niewoehner, Jens
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005765/
https://ncbi.nlm.nih.gov/pubmed/24788759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096340
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