Transmitted/Founder and Chronic Subtype C HIV-1 Use CD4 and CCR5 Receptors with Equal Efficiency and Are Not Inhibited by Blocking the Integrin α4β7

Sexual transmission of human immunodeficiency virus type 1 (HIV-1) most often results from productive infection by a single transmitted/founder (T/F) virus, indicating a stringent mucosal bottleneck. Understanding the viral traits that overcome this bottleneck could have important implications for H...

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Main Authors: Parrish, Nicholas F., Wilen, Craig B., Banks, Lauren B., Iyer, Shilpa S., Pfaff, Jennifer M., Salazar-Gonzalez, Jesus F., Salazar, Maria G., Decker, Julie M., Parrish, Erica H., Berg, Anna, Hopper, Jennifer, Hora, Bhavna, Kumar, Amit, Mahlokozera, Tatenda, Yuan, Sally, Coleman, Charl, Vermeulen, Marion, Ding, Haitao, Ochsenbauer, Christina, Tilton, John C., Permar, Sallie R., Kappes, John C., Betts, Michael R., Busch, Michael P., Gao, Feng, Montefiori, David, Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Doms, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364951/
https://ncbi.nlm.nih.gov/pubmed/22693444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002686
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