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The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes

Of all biochemically characterized metabolic reactions formalized by the IUBMB, over one out of four have yet to be associated with a nucleic or protein sequence, i.e. are sequence-orphan enzymatic activities. Few bioinformatics annotation tools are able to propose candidate genes for such activitie...

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Autores principales: Smith, Adam Alexander Thil, Belda, Eugeni, Viari, Alain, Medigue, Claudine, Vallenet, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364942/
https://ncbi.nlm.nih.gov/pubmed/22693442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002540
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