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Detecting and Analyzing DNA Sequencing Errors: Toward a Higher Quality of the Bacillus subtilis Genome Sequence

During the determination of a DNA sequence, the introduction of artifactual frameshifts and/or in-frame stop codons in putative genes can lead to misprediction of gene products. Detection of such errors with a method based on protein similarity matching is only possible when related sequences are av...

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Détails bibliographiques
Auteurs principaux: Médigue, Claudine, Rose, Matthias, Viari, Alain, Danchin, Antoine
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC310837/
https://ncbi.nlm.nih.gov/pubmed/10568751
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