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Improved negative selection protocol for Plasmodium berghei in the rodent malarial model

An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and substitutes delivery of selection drug 5-fluorocytosine...

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Autors principals: Orr, Rachael Y, Philip, Nisha, Waters, Andrew P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364864/
https://ncbi.nlm.nih.gov/pubmed/22463060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-103
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