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Upregulation of TLR1, TLR2, TLR4, and IRAK-2 Expression During ML-1 Cell Differentiation to Macrophages: Role in the Potentiation of Cellular Responses to LPS and LTA

12-O-tetradecanoylphorbol 13-acetate (TPA) induces the differentiation of human myeloid ML-1 cells to macrophages. In the current study, the expression, responsiveness, and regulation of toll-like receptors (TLRs) in TPA-induced ML-1-derived macrophages were investigated. We have found that TPA-indu...

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Detalhes bibliográficos
Main Authors: Traore, Kassim, Zirkin, Barry, Thimmulappa, Rajesh K., Biswal, Shyam, Trush, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Scholarly Research Network 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364600/
https://ncbi.nlm.nih.gov/pubmed/22685674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/641246
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