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Energetics and stereochemistry of DNA complexation with the antitumor AT specific intercalators tilorone and m-AMSA.
Computations by the SIBFA method on the intercalative interaction energies of tilorone and m-AMSA with B-DNA representative oligonucleotides account for the specificity of these antitumor drugs for AT sites and minor groove intercalation. In tilorone this specificity is due to the strong preference...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1988
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336452/ https://ncbi.nlm.nih.gov/pubmed/3368315 |
| Taggar: |
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