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Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility
PTEN (phosphatase and tensin homolog deleted on chromosome 10) functions as a major tumor suppressor gene and is frequently deleted in different types of tumors including prostate cancer (PCa). It was hypothesized that germ-line genetic changes of PTEN affect susceptibility to PCa. Both common (with...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364485/ https://ncbi.nlm.nih.gov/pubmed/21633361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2011.48 |
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