A genome-wide survey over the ChIP-on-chip identified androgen receptor binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13

BACKGROUND: The molecular mechanisms for the GWAS-identified prostate cancer (PCa) risk-associated SNPs remain largely unexplained. One recent finding that the PCa risk SNPs are enriched in genomic regions containing androgen receptor (AR) binding sites has suggested altered AR signaling as a potent...

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Autores principales: Feng, Junjie, Sun, Jielin, Kim, Seong-Tae, Lu, Yizhen, Wang, Zhong, Zhang, Zheng, Gronberg, Henrik, Isaacs, William B., Zheng, S. Lilly, Xu, Jianfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210915/
https://ncbi.nlm.nih.gov/pubmed/21960693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0523
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