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A genome-wide survey over the ChIP-on-chip identified androgen receptor binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13
BACKGROUND: The molecular mechanisms for the GWAS-identified prostate cancer (PCa) risk-associated SNPs remain largely unexplained. One recent finding that the PCa risk SNPs are enriched in genomic regions containing androgen receptor (AR) binding sites has suggested altered AR signaling as a potent...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210915/ https://ncbi.nlm.nih.gov/pubmed/21960693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0523 |
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