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Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft versus host disease
Cells generate ATP by glycolysis and by oxidative phosphorylation (OXPHOS) (1, 2). Despite the importance of having sufficient ATP available for the energy-dependent processes involved in immune activation, little is known about the metabolic adaptations that occur in vivo to meet the increased dema...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364290/ https://ncbi.nlm.nih.gov/pubmed/21270339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001975 |
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