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A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting
In yeast, the sorting of transmembrane proteins into the multivesicular body (MVB) internal vesicles requires their ubiquitylation by the ubiquitin ligase Rsp5. This allows their recognition by the ubiquitin-binding domains (UBDs) of several endosomal sorting complex required for transport (ESCRT) s...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364180/ https://ncbi.nlm.nih.gov/pubmed/22493318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0891 |
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