A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting

In yeast, the sorting of transmembrane proteins into the multivesicular body (MVB) internal vesicles requires their ubiquitylation by the ubiquitin ligase Rsp5. This allows their recognition by the ubiquitin-binding domains (UBDs) of several endosomal sorting complex required for transport (ESCRT) s...

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Bibliografiska uppgifter
Huvudupphovsmän: Erpapazoglou, Zoi, Dhaoui, Manel, Pantazopoulou, Marina, Giordano, Francesca, Mari, Muriel, Léon, Sébastien, Raposo, Graça, Reggiori, Fulvio, Haguenauer-Tsapis, Rosine
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364180/
https://ncbi.nlm.nih.gov/pubmed/22493318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0891
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