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Ear1p and Ssh4p Are New Adaptors of the Ubiquitin Ligase Rsp5p for Cargo Ubiquitylation and Sorting at Multivesicular Bodies

The ubiquitylation of membrane proteins destined for the vacuole/lysosome is essential for their recognition by the endosomal sorting machinery and their internalization into vesicles of multivesicular bodies (MVBs). In yeast, this process requires Rsp5p, an essential ubiquitin ligase of the Nedd4 f...

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Hlavní autoři: Léon, Sébastien, Erpapazoglou, Zoi, Haguenauer-Tsapis, Rosine
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397306/
https://ncbi.nlm.nih.gov/pubmed/18367543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0068
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