Evaluation of Diverse α/β Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain

Peptidic oligomers that contain both α- and β-amino acid residues, in regular patterns throughout the backbone, are emerging as structural mimics of α-helix-forming conventional peptides (composed exclusively of α-amino acid residues). Here we describe a comprehensive evaluation of diverse α/β-pepti...

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Main Authors: Boersma, Melissa D., Haase, Holly S., Peterson-Kaufman, Kimberly J., Lee, Erinna F., Clarke, Oliver B., Colman, Peter M., Smith, Brian J., Horne, W. Seth, Fairlie, W. Douglas, Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364022/
https://ncbi.nlm.nih.gov/pubmed/22040025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja207148m
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