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Sequence-specific binding of luzopeptin to DNA.
We have examined the binding of luzopeptin, an antitumor antibiotic, to five DNA fragments of varying base composition. The drug forms a tight, possibly covalent, complex with the DNA causing a reduction in mobility on nondenaturing polyacrylamide gels and some smearing of the bands consistent with...
Uloženo v:
| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1988
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336385/ https://ncbi.nlm.nih.gov/pubmed/3362673 |
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