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Sequence-selective binding of phleomycin to DNA.

The binding of phleomycin and bleomycin to DNA has been investigated by studying their effects on cleavage by DNAase I and micrococcal nuclease. In the presence of cobalt, cleavage of DNA by the antibiotics is suppressed, yet they still provide protection from nuclease attack in regions surrounding...

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Autors principals: Fox, K R, Grigg, G W, Waring, M J
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147934/
https://ncbi.nlm.nih.gov/pubmed/2444208
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