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Sequence-specific binding of echinomycin to DNA: evidence for conformational changes affecting flanking sequences.
The technique of DNAase I footprinting has been used to investigate preferred binding sites for echinomycin on a 160-base-pair DNA fragment from E. coli containing the tyr T promoter sequence. Six binding sites have been precisely located in the sequence; a seventh has been partially identified. The...
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| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1984
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC318885/ https://ncbi.nlm.nih.gov/pubmed/6204275 |
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