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Ontogeny of Novel Cytochrome P450 Gene Isoforms during Postnatal Liver Maturation in Mice

The ontogeny of the first four families of cytochromes P450 (P450s) (i.e., Cyp1–Cyp4) can affect the biotransformation of drugs and dietary chemicals in liver, resulting in unique pharmacological reactions in children. Because genome-scale investigations have identified many novel P450 isoforms, it...

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Bibliografske podrobnosti
Main Authors: Cui, Julia Yue, Renaud, Helen J., Klaassen, Curtis D.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362787/
https://ncbi.nlm.nih.gov/pubmed/22446519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042697
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