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Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice
Cytochrome P450 (Cyp) enzymes from the first four families (Cyp1–4) play a major role in metabolizing xenobiotics, affecting drug pharmacokinetics and chemical-induced toxicity. Due to cloning of the mouse genome, many novel Cyp isoforms have been identified, but their tissue distribution of express...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216415/ https://ncbi.nlm.nih.gov/pubmed/21920951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr240 |
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