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Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice
The induction of drug-metabolizing enzymes by chemicals is one of the major reasons for drug-drug interactions. In the present study, the regulation of mRNA expression of one arylacetamide deacetylase (Aadac) and 11 carboxylesterases (Cess) by 15 microsomal enzyme inducers (MEIs) was examined in liv...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362786/ https://ncbi.nlm.nih.gov/pubmed/22429928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.043877 |
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