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Sequence variability of immunoglobulins considered from the standpoint of population genetics

The probability of gene identity between members of a multigene family was investigated, assuming mutation, random genetic drift, and unequal crossing-over. The theoretical results on the equilibrium and transient behavior of the identity probability were applied to the analyses of sequence variabil...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Ohta, Tomoko
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.5108
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