Sequence variability of immunoglobulins considered from the standpoint of population genetics
The probability of gene identity between members of a multigene family was investigated, assuming mutation, random genetic drift, and unequal crossing-over. The theoretical results on the equilibrium and transient behavior of the identity probability were applied to the analyses of sequence variabil...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1978
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.5108 |
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