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Estimation of expected number of rare alleles of a locus and calculation of mutation rate

An approach is described for the estimation of the number of rare variants in the population from the number in a sample drawn at random from the population. This quantity is used to derive an estimate of the mutation rate. The data required are the number of rare variants in the sample and the dist...

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Detalhes bibliográficos
Main Authors: Rothman, Edward D., Adams, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC336270/
https://ncbi.nlm.nih.gov/pubmed/16592582
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