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Estimation of expected number of rare alleles of a locus and calculation of mutation rate

An approach is described for the estimation of the number of rare variants in the population from the number in a sample drawn at random from the population. This quantity is used to derive an estimate of the mutation rate. The data required are the number of rare variants in the sample and the dist...

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Main Authors: Rothman, Edward D., Adams, Julian
格式: Artigo
語言:Inglês
出版: 1978
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC336270/
https://ncbi.nlm.nih.gov/pubmed/16592582
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