Estimation of expected number of rare alleles of a locus and calculation of mutation rate
An approach is described for the estimation of the number of rare variants in the population from the number in a sample drawn at random from the population. This quantity is used to derive an estimate of the mutation rate. The data required are the number of rare variants in the sample and the dist...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1978
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.5094 |
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