Autoimmunity in CD73/Ecto-5′-Nucleotidase Deficient Mice Induces Renal Injury

Extracellular adenosine formed by 5′-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important immune modulator. Since CD73(−/−)mutant mice exhibit a vascular proinflammatory phenotype, we asked whether long term lack of CD73 causes inflamma...

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Main Authors: Blume, Cornelia, Felix, Agnieszka, Shushakova, Nelli, Gueler, Faikah, Falk, Christine Susanne, Haller, Hermann, Schrader, Juergen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362584/
https://ncbi.nlm.nih.gov/pubmed/22666342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037100
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