Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells.

Deoxyadenosine at low concentrations and in the presence of an inhibitor of adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) is markedly toxic to lymphoblast cell lines of T cell origin but does not impair growth of B cell lines. Deoxyguanosine is also more toxic for T lymphoblasts. In the...

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Detaylı Bibliyografya
Asıl Yazarlar: Mitchell, B S, Mejias, E, Daddona, P E, Kelley, W N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1978
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC336252/
https://ncbi.nlm.nih.gov/pubmed/311004
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